SafeSciMET course: Predictive Cell Culture Systems

Date: from 13-02-2012 to 17-02-2012

Address: Institute of Environmental Toxicology, Medical Faculty, Martin‐Luther‐University of Halle‐Wittenberg Franzosenweg 1a

ZIP: D‐06112

City: Halle/Saale

Country: Germany

This course is part of the programme developed under the Innovative Medicines Initiative, SafeSciMET, a public-private partnership between the European pharmaceutical industry (EFPIA) and European academia. All courses will have a mixed faculty of scientists from academia and industry and utilise case studies from industry. Courses are planned for the coming 2 years all over Europe.

The course will focus on Predictive Cell Culture Systems. It will cover the following themes:

Limits and strengths of permanent versus primary cells
Robust parameters to monitor cell functions
Early cellular responses to stressors
Test batteries for cytotoxicity and cellular dysfunction
Competence to cope with oxidative/cellular stress
Pathways of toxicity involving impairment of glutathione
Use of ‘omics technologies to identify critical pathways of toxicity
Cell cultures systems to detect substrates/inductors of cytochrome P 450/drug metabolizing enzymes
Search for drug targets versus drug safety using in vitro tests
Requirements on cell culture systems for screening /high throughput techniques
Alternative methods and regulatory requirements

The courses can be taken individually. Fee per course is €2,500 – 750 (dependent on category of student) with discount schemes for multiple courses. The courses meets the criteria for Continuous Professional Development (CPD) diplomas and they will be part of a forthcoming European Master of Advanced Safety Science Degree.

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SafeSciMET course: Predictive Cell Culture Systems

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